Below is a list of sources used in conducting my research and developing the project:
5X RIPA Buffer, with Protease Inhibitor Cocktail (2017) Retrieved from https://www.cellbiolabs.com/sites/default/files/AKR-190-ripa-buffer_0.pdf
Breast Cancer Statistics (n.d.) Retrieved from https://www.bcrf.org/breast-cancer-statistics
Cancer in the Sixteenth to Eigtheenth Centuries (2014) Retrieved from https://www.cancer.org/cancer/cancer-basics/history-of-cancer/sixteenth-to-eighteenth-centuries.html
Cancer Statistics (2018) Retrieved from https://www.cancer.gov/about-cancer/understanding/statistics
Cao, M. D., Cheng, M., Rizwan, A., Jiang, L., Krishnamachary, B., Bhujwalla, Z. M., … Glunde, K. (2016). Targeting choline phospholipid metabolism: GDPD5 and GDPD6 silencing decrease breast cancer cell proliferation, migration, and invasion. NMR in Biomedicine, 29(8), 1098–1107. http://doi.org/10.1002/nbm.3573
Cellular Respiration (2004) Retrieved from https://www.biology.iupui.edu/biocourses/N100/2k4ch7respirationnotes.html
Cheng, M., Bhujwalla, Z. M., & Glunde, K. (2016). Targeting Phospholipid Metabolism in Cancer. Frontiers in oncology, 6, 266. doi:10.3389/fonc.2016.00266
Daly, P., Lyon, R., Faustino, P., Cohen, J. (1987). Phospholipid metabolism in cancer cells monitored by 31P NMR spectroscopy. Journal of Biological Chemistry, 262(31), 14875-14878. Doi: 3667610
DeBerardinis et al. (2008) The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation. ScienceDirect, 7(1), 11-20. Doi: https://doi.org/10.1016/j.cmet.2007.10.002
Early History of Cancer (2014) Retrieved from https://www.cancer.org/cancer/cancer-basics/history-of-cancer/what-is-cancer.html
Glunde, K., Bhujwalla, Z. M., & Ronen, S. M. (2011). Choline metabolism in malignant transformation. Nature Reviews. Cancer, 11(12), 835–848. http://doi.org/10.1038/nrc3162
Goldhirsch, A., Wood, W. C., Coates, A. S., Gelber, R. D., Thürlimann, B., Senn, H.-J., & Panel members. (2011). Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Annals of Oncology, 22(8), 1736–1747. http://doi.org/10.1093/annonc/mdr304
How Common Is Breast Cancer? (2017) Retrieved from https://www.cancer.org/cancer/breast-cancer/about/how-common-is-breast-cancer.html
How DNA Microarrays Work (n.d.) Retrieved from http://www.pbs.org/wgbh/nova/education/activities/3413_genes_02.html
Jia, M., Andreassen, T., Jensen, L., Bathen, T. F., Sinha, I., Gao, H., . . . Dahlman-Wright, K. (2016). Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism. Cancer Research, 76(19), 5634-5646. doi:10.1158/0008-5472.can-15-2910
Kim et al. (2006). HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Press, 3(3), 177-185. https://doi.org/10.1016/j.cmet.2006.02.002
Mahmood, T., & Yang, P.-C. (2012). Western Blot: Technique, Theory, and Trouble Shooting. North American Journal of Medical Sciences, 4(9), 429–434. http://doi.org/10.4103/1947-2714.100998
Missmer, S. A., Eliassen, A. H., Barbieri, R. L., & Hankinson, S. E. (2004). Endogenous Estrogen, Androgen, and Progesterone Concentrations and Breast Cancer Risk Among Postmenopausal Women. JNCI Journal of the National Cancer Institute, 96(24), 1856-1865. doi:10.1093/jnci/djh336
Moestue, S. A., Giskeødegård, G. F., Cao, M. D., Bathen, T. F., & Gribbestad, I. S. (2012). Glycerophosphocholine (GPC) is a poorly understood biomarker in breast cancer. Proceedings of the National Academy of Sciences of the United States of America, 109(38), E2506; author reply E2507.
Patrick S. Ward, Craig B. Thompson, (2012). Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate, Cancer Cell, Volume 21, Issue 3, Pages 297-308, ISSN 1535-6108, https://doi.org/10.1016/j.ccr.2012.02.014.
Pinton et al. (2018). Targeting estrogen receptor beta (ERβ) for treatment of ovarian cancer: importance of KDM6B and SIRT1 for ERβ expression and functionality. Nature, Oncogenesis (15). https://doi.org/10.1038/s41389-018-0027-9DO
Overview of Western Blotting (n.d.) Retrieved from https://www.thermofisher.com/us/en/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/pierce-protein-methods/overview-western-blotting.html
Semenza, Gregg (2016). Hypoxia-inducible Factors: Coupling Glucose Metabolism and Redox Regulation with Induction of the Breast Cancer Stem Cell Phenotype, Embo Journal, Volume 36, Issue 3, doi: 10.15252/embj.201695204
Sotiriou, C., Pusztai, L. (2009). Gene-Expression Signatures in Breast Cancer, New England Journal of Medicine, 360;8, doi: 10.1056/NEJMra0801289
Sparano et al. (2018). Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer, New England Journal of Medicine (ePrint) doi: 10.1056/NEJMoa1804710
TBST for Western Blotting (2013) Retrieved from http://cshprotocols.cshlp.org/content/2013/3/pdb.rec074104.full?text_only=true
U.S. Breast Cancer Statistics (2018) Retrieved from http://www.breastcancer.org/symptoms/understand_bc/statistics
Vijver et al (2002). A Gene-Expression Signature as a Predictor of Survival in Breast Cancer, New England Journal of Medicine, 347:1999-2009, doi:10.1056/NEJMoa021967
Wang, R., Dillon, C. P., Shi, L. Z., Milasta, S., Carter, R., Finkelstein, D., … Green, D. R. (2011). The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity, 35(6), 871–882. http://doi.org/10.1016/j.immuni.2011.09.021
What is Cancer? (2015) Retrieved from https://www.cancer.gov/about-cancer/understanding/what-is-cancer
Wijnen, J. P., Jiang, L., Greenwood, T. R., Cheng, M., Döpkens, M., Cao, M. D., Bhujwalla, Z. M., Krishnamachary, B., Klomp, D. W., … Glunde, K. (2014). Silencing of the glycerophosphocholine phosphodiesterase GDPD5 alters the phospholipid metabolite profile in a breast cancer model in vivo as monitored by (31) P MRS. NMR in biomedicine, 27(6), 692-9.
Zhong et al. (1999). Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. American Association for Cancer Research, 59(22), 5830-1835. Doi: 10582706
Ziello, J. E., Jovin, I. S., & Huang, Y. (2007). Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway and its Potential for Therapeutic Intervention in Malignancy and Ischemia. The Yale Journal of Biology and Medicine, 80(2), 51–60. Doi: PMC2140184
5X RIPA Buffer, with Protease Inhibitor Cocktail (2017) Retrieved from https://www.cellbiolabs.com/sites/default/files/AKR-190-ripa-buffer_0.pdf
Breast Cancer Statistics (n.d.) Retrieved from https://www.bcrf.org/breast-cancer-statistics
Cancer in the Sixteenth to Eigtheenth Centuries (2014) Retrieved from https://www.cancer.org/cancer/cancer-basics/history-of-cancer/sixteenth-to-eighteenth-centuries.html
Cancer Statistics (2018) Retrieved from https://www.cancer.gov/about-cancer/understanding/statistics
Cao, M. D., Cheng, M., Rizwan, A., Jiang, L., Krishnamachary, B., Bhujwalla, Z. M., … Glunde, K. (2016). Targeting choline phospholipid metabolism: GDPD5 and GDPD6 silencing decrease breast cancer cell proliferation, migration, and invasion. NMR in Biomedicine, 29(8), 1098–1107. http://doi.org/10.1002/nbm.3573
Cellular Respiration (2004) Retrieved from https://www.biology.iupui.edu/biocourses/N100/2k4ch7respirationnotes.html
Cheng, M., Bhujwalla, Z. M., & Glunde, K. (2016). Targeting Phospholipid Metabolism in Cancer. Frontiers in oncology, 6, 266. doi:10.3389/fonc.2016.00266
Daly, P., Lyon, R., Faustino, P., Cohen, J. (1987). Phospholipid metabolism in cancer cells monitored by 31P NMR spectroscopy. Journal of Biological Chemistry, 262(31), 14875-14878. Doi: 3667610
DeBerardinis et al. (2008) The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation. ScienceDirect, 7(1), 11-20. Doi: https://doi.org/10.1016/j.cmet.2007.10.002
Early History of Cancer (2014) Retrieved from https://www.cancer.org/cancer/cancer-basics/history-of-cancer/what-is-cancer.html
Glunde, K., Bhujwalla, Z. M., & Ronen, S. M. (2011). Choline metabolism in malignant transformation. Nature Reviews. Cancer, 11(12), 835–848. http://doi.org/10.1038/nrc3162
Goldhirsch, A., Wood, W. C., Coates, A. S., Gelber, R. D., Thürlimann, B., Senn, H.-J., & Panel members. (2011). Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Annals of Oncology, 22(8), 1736–1747. http://doi.org/10.1093/annonc/mdr304
How Common Is Breast Cancer? (2017) Retrieved from https://www.cancer.org/cancer/breast-cancer/about/how-common-is-breast-cancer.html
How DNA Microarrays Work (n.d.) Retrieved from http://www.pbs.org/wgbh/nova/education/activities/3413_genes_02.html
Jia, M., Andreassen, T., Jensen, L., Bathen, T. F., Sinha, I., Gao, H., . . . Dahlman-Wright, K. (2016). Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism. Cancer Research, 76(19), 5634-5646. doi:10.1158/0008-5472.can-15-2910
Kim et al. (2006). HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Press, 3(3), 177-185. https://doi.org/10.1016/j.cmet.2006.02.002
Mahmood, T., & Yang, P.-C. (2012). Western Blot: Technique, Theory, and Trouble Shooting. North American Journal of Medical Sciences, 4(9), 429–434. http://doi.org/10.4103/1947-2714.100998
Missmer, S. A., Eliassen, A. H., Barbieri, R. L., & Hankinson, S. E. (2004). Endogenous Estrogen, Androgen, and Progesterone Concentrations and Breast Cancer Risk Among Postmenopausal Women. JNCI Journal of the National Cancer Institute, 96(24), 1856-1865. doi:10.1093/jnci/djh336
Moestue, S. A., Giskeødegård, G. F., Cao, M. D., Bathen, T. F., & Gribbestad, I. S. (2012). Glycerophosphocholine (GPC) is a poorly understood biomarker in breast cancer. Proceedings of the National Academy of Sciences of the United States of America, 109(38), E2506; author reply E2507.
Patrick S. Ward, Craig B. Thompson, (2012). Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate, Cancer Cell, Volume 21, Issue 3, Pages 297-308, ISSN 1535-6108, https://doi.org/10.1016/j.ccr.2012.02.014.
Pinton et al. (2018). Targeting estrogen receptor beta (ERβ) for treatment of ovarian cancer: importance of KDM6B and SIRT1 for ERβ expression and functionality. Nature, Oncogenesis (15). https://doi.org/10.1038/s41389-018-0027-9DO
Overview of Western Blotting (n.d.) Retrieved from https://www.thermofisher.com/us/en/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/pierce-protein-methods/overview-western-blotting.html
Semenza, Gregg (2016). Hypoxia-inducible Factors: Coupling Glucose Metabolism and Redox Regulation with Induction of the Breast Cancer Stem Cell Phenotype, Embo Journal, Volume 36, Issue 3, doi: 10.15252/embj.201695204
Sotiriou, C., Pusztai, L. (2009). Gene-Expression Signatures in Breast Cancer, New England Journal of Medicine, 360;8, doi: 10.1056/NEJMra0801289
Sparano et al. (2018). Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer, New England Journal of Medicine (ePrint) doi: 10.1056/NEJMoa1804710
TBST for Western Blotting (2013) Retrieved from http://cshprotocols.cshlp.org/content/2013/3/pdb.rec074104.full?text_only=true
U.S. Breast Cancer Statistics (2018) Retrieved from http://www.breastcancer.org/symptoms/understand_bc/statistics
Vijver et al (2002). A Gene-Expression Signature as a Predictor of Survival in Breast Cancer, New England Journal of Medicine, 347:1999-2009, doi:10.1056/NEJMoa021967
Wang, R., Dillon, C. P., Shi, L. Z., Milasta, S., Carter, R., Finkelstein, D., … Green, D. R. (2011). The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity, 35(6), 871–882. http://doi.org/10.1016/j.immuni.2011.09.021
What is Cancer? (2015) Retrieved from https://www.cancer.gov/about-cancer/understanding/what-is-cancer
Wijnen, J. P., Jiang, L., Greenwood, T. R., Cheng, M., Döpkens, M., Cao, M. D., Bhujwalla, Z. M., Krishnamachary, B., Klomp, D. W., … Glunde, K. (2014). Silencing of the glycerophosphocholine phosphodiesterase GDPD5 alters the phospholipid metabolite profile in a breast cancer model in vivo as monitored by (31) P MRS. NMR in biomedicine, 27(6), 692-9.
Zhong et al. (1999). Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. American Association for Cancer Research, 59(22), 5830-1835. Doi: 10582706
Ziello, J. E., Jovin, I. S., & Huang, Y. (2007). Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway and its Potential for Therapeutic Intervention in Malignancy and Ischemia. The Yale Journal of Biology and Medicine, 80(2), 51–60. Doi: PMC2140184